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Effect of sex on the APOE4-aging interaction in the white matter microstructure of cognitively normal older adults using diffusion-tensor MRI with orthogonal-tensor decomposition (DT-DOME)

The influence of the apolipoprotein E ε4 allele (APOE4) on brain microstructure of cognitively normal older adults remains incompletely understood, in part due to heterogeneity within study populations. In this study, we examined white-matter microstructural integrity in cognitively normal older adu...

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Detalles Bibliográficos
Autores principales: Srisaikaew, Patcharaporn, Chad, Jordan A., Mahakkanukrauh, Pasuk, Anderson, Nicole D., Chen, J. Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992882/
https://www.ncbi.nlm.nih.gov/pubmed/36908785
http://dx.doi.org/10.3389/fnins.2023.1049609