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The TUDOR domain of SMN is an H3K79(me1) histone mark reader

Spinal muscular atrophy is the leading genetic cause of infant mortality and results from depleted levels of functional survival of motor neuron (SMN) protein by either deletion or mutation of the SMN1 gene. SMN is characterized by a central TUDOR domain, which mediates the association of SMN with a...

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Detalles Bibliográficos
Autores principales: Binda, Olivier, Kimenyi Ishimwe, Aimé Boris, Galloy, Maxime, Jacquet, Karine, Corpet, Armelle, Fradet-Turcotte, Amélie, Côté, Jocelyn, Lomonte, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993015/
https://www.ncbi.nlm.nih.gov/pubmed/36882285
http://dx.doi.org/10.26508/lsa.202201752