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Deaminative bromination, chlorination, and iodination of primary amines

The primary amino group has been seldom utilized as a transformable functionality in organic synthesis. Reported herein is a deaminative halogenation of primary amines using N-anomeric amide as the nitrogen-deletion reagent. Both aliphatic and aromatic amines are competent substrates for direct halo...

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Detalles Bibliográficos
Autores principales: Xue, Jiang-Hao, Li, Yin, Tan, Dong-Hang, Tu, Fang-Hai, Liu, Yuan, Li, Qingjiang, Wang, Honggen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993034/
https://www.ncbi.nlm.nih.gov/pubmed/36909668
http://dx.doi.org/10.1016/j.isci.2023.106255