D-Serine reduces the expression of the cytopathic genotoxin colibactin

Some Escherichia coli strains harbour the pks island, a 54 kb genomic island encoding the biosynthesis genes for a genotoxic compound named colibactin. In eukaryotic cells, colibactin can induce DNA damage, cell cycle arrest and chromosomal instability. Production of colibactin has been implicated i...

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Detalles Bibliográficos
Autores principales: Hallam, Jennifer C., Sandalli, Sofia, Floria, Iris, Turner, Natasha C. A., Tang-Fichaux, Min, Oswald, Eric, O'Boyle, Nicky, Roe, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993432/
https://www.ncbi.nlm.nih.gov/pubmed/36908282
http://dx.doi.org/10.15698/mic2023.03.793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993432/
https://www.ncbi.nlm.nih.gov/pubmed/36908282
http://dx.doi.org/10.15698/mic2023.03.793

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