Dimethyl itaconate is effective in host-directed antimicrobial responses against mycobacterial infections through multifaceted innate immune pathways

BACKGROUND: Itaconate, a crucial immunometabolite, plays a critical role in linking immune and metabolic functions to influence host defense and inflammation. Due to its polar structure, the esterified cell-permeable derivatives of itaconate are being developed to provide therapeutic opportunities i...

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Detalles Bibliográficos
Autores principales: Kim, Young Jae, Park, Eun-Jin, Lee, Sang-Hee, Silwal, Prashanta, Kim, Jin Kyung, Yang, Jeong Seong, Whang, Jake, Jang, Jichan, Kim, Jin-Man, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993662/
https://www.ncbi.nlm.nih.gov/pubmed/36882813
http://dx.doi.org/10.1186/s13578-023-00992-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993662/
https://www.ncbi.nlm.nih.gov/pubmed/36882813
http://dx.doi.org/10.1186/s13578-023-00992-x

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