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Membrane-tethered activation design of a photosensitizer boosts systemic antitumor immunity via pyroptosis

Pyroptotic immunogenic cell death presents an emerging targeting pathway for cancer immunotherapy. We report a novel membrane-tethered activation design of a photosensitizer (PS) that boosts systemic anti-tumor immunity to primary and distant tumors via pyroptosis induction. The membrane-tethered PS...

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Detalles Bibliográficos
Autores principales: Lu, Pei, Liu, Xianjun, Chu, Xia, Wang, Fenglin, Jiang, Jian-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993848/
https://www.ncbi.nlm.nih.gov/pubmed/36908949
http://dx.doi.org/10.1039/d2sc07044h