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Improved production of class I lanthipeptides in Escherichia coli

Lanthipeptides are ribosomally synthesised and post-translationally modified peptides containing lanthionine (Lan) and methyllanthionine (MeLan) residues that are formed by dehydration of Ser/Thr residues followed by conjugate addition of Cys to the resulting dehydroamino acids. Class I lanthipeptid...

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Detalles Bibliográficos
Autores principales: Lee, Hyunji, Wu, Chunyu, Desormeaux, Emily K., Sarksian, Raymond, van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9993889/
https://www.ncbi.nlm.nih.gov/pubmed/36908960
http://dx.doi.org/10.1039/d2sc06597e