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Protein–protein interfaces in molecular glue-induced ternary complexes: classification, characterization, and prediction

Molecular glues are a class of small molecules that stabilize the interactions between proteins. Naturally occurring molecular glues are present in many areas of biology where they serve as central regulators of signaling pathways. Importantly, several clinical compounds act as molecular glue degrad...

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Detalles Bibliográficos
Autores principales: Rui, Huan, Ashton, Kate S., Min, Jaeki, Wang, Connie, Potts, Patrick Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994104/
https://www.ncbi.nlm.nih.gov/pubmed/36908699
http://dx.doi.org/10.1039/d2cb00207h