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Substrate selectivity and inhibition of histidine JmjC hydroxylases MINA53 and NO66

Non-haem Fe(ii) and 2-oxoglutarate (2OG) dependent oxygenases catalyse oxidation of multiple proteins in organisms ranging from bacteria to humans. We describe studies on the substrate selectivity and inhibition of the human ribosomal oxygenases (ROX) MINA53 and NO66, members of the JmjC 2OG oxygena...

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Detalles Bibliográficos
Autores principales: Türkmen, Vildan A., Hintzen, Jordi C. J., Tumber, Anthony, Moesgaard, Laust, Salah, Eidarus, Kongsted, Jacob, Schofield, Christopher J., Mecinović, Jasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994133/
https://www.ncbi.nlm.nih.gov/pubmed/36908702
http://dx.doi.org/10.1039/d2cb00182a