Streptococcus pneumoniae carriage studies in adults: Importance, challenges, and key issues to consider when using quantitative PCR-based approaches

Streptococcus pneumoniae causes significant morbidity and mortality among older adults. Detection of pneumococcal carriage is an accepted endpoint in pneumococcal conjugate vaccine studies. However, low sensitivity of culture-based approaches and nasopharyngeal samples have hampered adult S. pneumon...

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Detalles Bibliográficos
Autores principales: Miellet, Willem R., Almeida, Sónia T., Trzciński, Krzysztof, Sá-Leão, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994646/
https://www.ncbi.nlm.nih.gov/pubmed/36910231
http://dx.doi.org/10.3389/fmicb.2023.1122276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994646/
https://www.ncbi.nlm.nih.gov/pubmed/36910231
http://dx.doi.org/10.3389/fmicb.2023.1122276

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