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Development and validation of small animal models for onchocerciasis and loiasis microfilaricide discovery

BACKGROUND: Onchocerciasis (river blindness) caused by the filarial worm Onchocerca volvulus is a neglected tropical disease that affects the skin and eyes of humans. Mass drug administration with ivermectin (IVM) to control the disease often suffers from severe adverse events in individuals co-inje...

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Detalles Bibliográficos
Autores principales: Ayiseh, Rene Bilingwe, Mbah, Glory Enjong, Monya, Elvis, Ndi, Emmanuel Menang, Sakanari, Judy, Lustigman, Sara, Cho-Ngwa, Fidelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994675/
https://www.ncbi.nlm.nih.gov/pubmed/36827447
http://dx.doi.org/10.1371/journal.pntd.0011135