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Development and validation of small animal models for onchocerciasis and loiasis microfilaricide discovery
BACKGROUND: Onchocerciasis (river blindness) caused by the filarial worm Onchocerca volvulus is a neglected tropical disease that affects the skin and eyes of humans. Mass drug administration with ivermectin (IVM) to control the disease often suffers from severe adverse events in individuals co-inje...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994675/ https://www.ncbi.nlm.nih.gov/pubmed/36827447 http://dx.doi.org/10.1371/journal.pntd.0011135 |