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SARS-CoV-2 spike protein-mediated cardiomyocyte fusion may contribute to increased arrhythmic risk in COVID-19

BACKGROUND: SARS-CoV-2-mediated COVID-19 may cause sudden cardiac death (SCD). Factors contributing to this increased risk of potentially fatal arrhythmias include thrombosis, exaggerated immune response, and treatment with QT-prolonging drugs. However, the intrinsic arrhythmic potential of direct S...

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Detalles Bibliográficos
Autores principales: Clemens, Daniel J., Ye, Dan, Zhou, Wei, Kim, C. S. John, Pease, David R., Navaratnarajah, Chanakha K., Barkhymer, Alison, Tester, David J., Nelson, Timothy J., Cattaneo, Roberto, Schneider, Jay W., Ackerman, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994677/
https://www.ncbi.nlm.nih.gov/pubmed/36888581
http://dx.doi.org/10.1371/journal.pone.0282151