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Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE(−/−) mice

Chronic low-grade inflammation is regarded to an important signature of atherosclerosis (AS). Macrophage (Mψ) and related polarization have been demonstrated to play a crucial role in the occurrence and development of AS inflammation. Butyrate, a bioactive molecule produced by the intestinal flora,...

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Detalles Bibliográficos
Autores principales: Ma, Huiyan, Yang, Libo, Liu, Yajuan, Yan, Ru, Wang, Rui, Zhang, Peng, Bai, Zhixia, Liu, Yuanyuan, Ren, Yi, Li, Yiwei, Jiang, Xin, Wang, Ting, Ma, Ping, Zhang, Qining, Li, Aifei, Guo, Mixue, Zhang, Xiaoxia, Jia, Shaobin, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994734/
https://www.ncbi.nlm.nih.gov/pubmed/36888629
http://dx.doi.org/10.1371/journal.pone.0282685