Induction of fetal hemoglobin: Lentiviral shRNA knockdown of HBS1L in β(0)-thalassemia/HbE erythroid cells

Imbalanced globin chain output contributes to thalassemia pathophysiology. Hence, induction of fetal hemoglobin in β-thalassemia and other β-hemoglobinopathies are of continuing interest for therapeutic approaches. Genome-wide association studies have identified three common genetic loci: namely β-g...

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Detalles Bibliográficos
Autores principales: Chumchuen, Sukanya, Sripichai, Orapan, Jearawiriyapaisarn, Natee, Fucharoen, Suthat, Peerapittayamongkol, Chayanon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994754/
https://www.ncbi.nlm.nih.gov/pubmed/36888630
http://dx.doi.org/10.1371/journal.pone.0281059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994754/
https://www.ncbi.nlm.nih.gov/pubmed/36888630
http://dx.doi.org/10.1371/journal.pone.0281059

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