B cells promote granulomatous inflammation during chronic Mycobacterium tuberculosis infection in mice

The current study reveals that in chronic TB, the B cell-deficient μMT strain, relative to wild-type (WT) C57BL/6 mice, displays in the lungs lower levels of inflammation that are associated with decreased CD4(+) T cell proliferation, diminished Th1 response, and enhanced levels of interleukin (IL)-...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yong, Bharrhan, Sushma, Xu, Jiayong, Sharma, Tarina, Wang, Yanhua, Salgame, Padmini, Zhang, Jinghang, Nargan, Kievershen, Steyn, Adrie J. C., Maglione, Paul J., Chan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994760/
https://www.ncbi.nlm.nih.gov/pubmed/36888692
http://dx.doi.org/10.1371/journal.ppat.1011187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994760/
https://www.ncbi.nlm.nih.gov/pubmed/36888692
http://dx.doi.org/10.1371/journal.ppat.1011187

Ejemplares similares