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B cells promote granulomatous inflammation during chronic Mycobacterium tuberculosis infection in mice
The current study reveals that in chronic TB, the B cell-deficient μMT strain, relative to wild-type (WT) C57BL/6 mice, displays in the lungs lower levels of inflammation that are associated with decreased CD4(+) T cell proliferation, diminished Th1 response, and enhanced levels of interleukin (IL)-...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994760/ https://www.ncbi.nlm.nih.gov/pubmed/36888692 http://dx.doi.org/10.1371/journal.ppat.1011187 |