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Sloppiness: Fundamental study, new formalism and its application in model assessment

Computational modelling of biological processes poses multiple challenges in each stage of the modelling exercise. Some significant challenges include identifiability, precisely estimating parameters from limited data, informative experiments and anisotropic sensitivity in the parameter space. One o...

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Detalles Bibliográficos
Autores principales: Jagadeesan, Prem, Raman, Karthik, Tangirala, Arun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994762/
https://www.ncbi.nlm.nih.gov/pubmed/36888634
http://dx.doi.org/10.1371/journal.pone.0282609