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Sloppiness: Fundamental study, new formalism and its application in model assessment
Computational modelling of biological processes poses multiple challenges in each stage of the modelling exercise. Some significant challenges include identifiability, precisely estimating parameters from limited data, informative experiments and anisotropic sensitivity in the parameter space. One o...
Autores principales: | Jagadeesan, Prem, Raman, Karthik, Tangirala, Arun K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994762/ https://www.ncbi.nlm.nih.gov/pubmed/36888634 http://dx.doi.org/10.1371/journal.pone.0282609 |
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