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MetaProFi: an ultrafast chunked Bloom filter for storing and querying protein and nucleotide sequence data for accurate identification of functionally relevant genetic variants

MOTIVATION: Bloom filters are a popular data structure that allows rapid searches in large sequence datasets. So far, all tools work with nucleotide sequences; however, protein sequences are conserved over longer evolutionary distances, and only mutations on the protein level may have any functional...

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Detalles Bibliográficos
Autores principales: Srikakulam, Sanjay K, Keller, Sebastian, Dabbaghie, Fawaz, Bals, Robert, Kalinina, Olga V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994790/
https://www.ncbi.nlm.nih.gov/pubmed/36825843
http://dx.doi.org/10.1093/bioinformatics/btad101