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Does low-density lipoprotein fully explain atherosclerotic risk in familial hypercholesterolemia?

Familial hypercholesterolemia (FH) is a monogenic disorder of elevated low-density lipoprotein cholesterol (LDL-C) from birth leading to increased risk for atherosclerotic cardiovascular disease. However, not all carriers of FH variants display an FH phenotype. Despite this fact, FH variants confer...

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Detalles Bibliográficos
Autor principal: Clarke, Shoa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994798/
https://www.ncbi.nlm.nih.gov/pubmed/36853849
http://dx.doi.org/10.1097/MOL.0000000000000868