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Does low-density lipoprotein fully explain atherosclerotic risk in familial hypercholesterolemia?

Familial hypercholesterolemia (FH) is a monogenic disorder of elevated low-density lipoprotein cholesterol (LDL-C) from birth leading to increased risk for atherosclerotic cardiovascular disease. However, not all carriers of FH variants display an FH phenotype. Despite this fact, FH variants confer...

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Detalles Bibliográficos
Autor principal:	Clarke, Shoa L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	GENETICS & MOLECULAR BIOLOGY: Edited by Robert Hegele
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994798/ https://www.ncbi.nlm.nih.gov/pubmed/36853849 http://dx.doi.org/10.1097/MOL.0000000000000868

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