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Ectopic expression of SARS-CoV-2 S and ORF-9B proteins alters metabolic profiles and impairs contractile function in cardiomyocytes

Coronavirus disease 2019 (COVID-19) is associated with adverse impacts in the cardiovascular system, but the mechanisms driving this response remain unclear. In this study, we conducted “pseudoviral infection” of SARS-CoV-2 subunits to evaluate their toxic effects in cardiomyocytes (CMs), that were...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Liu, Yu, Li, Chunfeng, Stine, Lindsay D., Wang, Pei-Hui, Turnbull, Matthew W., Wu, Haodi, Liu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9994814/
https://www.ncbi.nlm.nih.gov/pubmed/36910162
http://dx.doi.org/10.3389/fcell.2023.1110271