Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity

Tumors use multiple mechanisms to actively exclude immune cells involved in antitumor immunity. Strategies to overcome these exclusion signals remain limited due to an inability to target therapeutics specifically to the tumor. Synthetic biology enables engineering of cells and microbes for tumor-lo...

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Detalles Bibliográficos
Autores principales: Savage, Thomas M., Vincent, Rosa L., Rae, Sarah S., Huang, Lei Haley, Ahn, Alexander, Pu, Kelly, Li, Fangda, de los Santos-Alexis, Kenia, Coker, Courtney, Danino, Tal, Arpaia, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995032/
https://www.ncbi.nlm.nih.gov/pubmed/36888717
http://dx.doi.org/10.1126/sciadv.adc9436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995032/
https://www.ncbi.nlm.nih.gov/pubmed/36888717
http://dx.doi.org/10.1126/sciadv.adc9436

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