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Dynamic bioinspired coculture model for probing ER(+) breast cancer dormancy in the bone marrow niche

Late recurrences of breast cancer are hypothesized to arise from disseminated tumor cells (DTCs) that reactivate after dormancy and occur most frequently with estrogen receptor–positive (ER(+)) breast cancer cells (BCCs) in bone marrow (BM). Interactions between the BM niche and BCCs are thought to...

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Detalles Bibliográficos
Autores principales: Pradhan, Lina, Moore, DeVonte, Ovadia, Elisa M., Swedzinski, Samantha L., Cossette, Travis, Sikes, Robert A., van Golen, Kenneth, Kloxin, April M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995072/
https://www.ncbi.nlm.nih.gov/pubmed/36888709
http://dx.doi.org/10.1126/sciadv.ade3186