Rational polyelectrolyte nanoparticles endow preosteoclast-targeted siRNA transfection for anabolic therapy of osteoporosis

Targeted transfection of siRNA to preosteoclasts features the potential of anti-osteoporosis, yet challenge arises from the development of satisfied delivery vehicles. Here, we design a rational core-shell nanoparticle (NP) composed of cationic and responsive core for controlled load and release of...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng, Ding, Peng, Meng, Yichen, Lin, Tao, Zhang, Zhanrong, Shu, Haoming, Ma, Jun, Cohen Stuart, Martien, Gao, Yang, Wang, Junyou, Zhou, Xuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995075/
https://www.ncbi.nlm.nih.gov/pubmed/36888701
http://dx.doi.org/10.1126/sciadv.ade7379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995075/
https://www.ncbi.nlm.nih.gov/pubmed/36888701
http://dx.doi.org/10.1126/sciadv.ade7379

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