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Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis

Cyclic AMP (cAMP) is a ubiquitous second messenger that transduces signals from cellular receptors to downstream effectors. Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis, devotes a considerable amount of coding capacity to produce, sense, and degrade cAMP. Despite this fact...

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Detalles Bibliográficos
Autores principales: Wong, Andrew I, Beites, Tiago, Planck, Kyle A, Fieweger, Rachael A, Eckartt, Kathryn A, Li, Shuqi, Poulton, Nicholas C, VanderVen, Brian C, Rhee, Kyu Y, Schnappinger, Dirk, Ehrt, Sabine, Rock, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995111/
https://www.ncbi.nlm.nih.gov/pubmed/36810158
http://dx.doi.org/10.7554/eLife.81177