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Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation

The glymphatic system is a fluid transport network of cerebrospinal fluid (CSF) entering the brain along arterial perivascular spaces, exchanging with interstitial fluid (ISF), ultimately establishing directional clearance of interstitial solutes. CSF transport is facilitated by the expression of aq...

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Detalles Bibliográficos
Autores principales: Gomolka, Ryszard Stefan, Hablitz, Lauren M, Mestre, Humberto, Giannetto, Michael, Du, Ting, Hauglund, Natalie Linea, Xie, Lulu, Peng, Weiguo, Martinez, Paula Melero, Nedergaard, Maiken, Mori, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995113/
https://www.ncbi.nlm.nih.gov/pubmed/36757363
http://dx.doi.org/10.7554/eLife.82232