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Zinc finger protein 521 attenuates osteoarthritis via the histone deacetylases 4 in the nucleus

To determine whether zinc finger protein 521 (Zfp521) has a chondroprotective effect by maintaining extracellular matrix (ECM) homeostasis to attenuate osteoarthritis (OA). In chondrocytes, Zfp521 was overexpressed or silenced to detect its effects on proliferation, apoptosis, and ECM homeostasis. A...

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Detalles Bibliográficos
Autores principales: Huang, Lingan, Li, Pengcui, Guo, Li, Li, Lu, Yuan, Jie, Zhao, Ruipeng, Li, Haoqian, Wei, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995124/
https://www.ncbi.nlm.nih.gov/pubmed/36694467
http://dx.doi.org/10.1080/21655979.2022.2090203