Cargando…
Zinc finger protein 521 attenuates osteoarthritis via the histone deacetylases 4 in the nucleus
To determine whether zinc finger protein 521 (Zfp521) has a chondroprotective effect by maintaining extracellular matrix (ECM) homeostasis to attenuate osteoarthritis (OA). In chondrocytes, Zfp521 was overexpressed or silenced to detect its effects on proliferation, apoptosis, and ECM homeostasis. A...
Autores principales: | Huang, Lingan, Li, Pengcui, Guo, Li, Li, Lu, Yuan, Jie, Zhao, Ruipeng, Li, Haoqian, Wei, Xiaochun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995124/ https://www.ncbi.nlm.nih.gov/pubmed/36694467 http://dx.doi.org/10.1080/21655979.2022.2090203 |
Ejemplares similares
-
Gait Analysis of Bilateral Knee Osteoarthritis and Its Correlation with Western Ontario and McMaster University Osteoarthritis Index Assessment
por: Li, Haoqian, et al.
Publicado: (2022) -
Zfp521 works its zinc fingers to the bone
por: Short, Ben
Publicado: (2010) -
Decreased histone deacetylase 4 is associated with human osteoarthritis cartilage degeneration by releasing histone deacetylase 4 inhibition of runt-related transcription factor-2 and increasing osteoarthritis-related genes: a novel mechanism of human osteoarthritis cartilage degeneration
por: Cao, Kun, et al.
Publicado: (2014) -
The Level of Histone Deacetylase 4 is Associated with Aging Cartilage Degeneration and Chondrocyte Hypertrophy
por: Dong, Zhengquan, et al.
Publicado: (2022) -
Abnormal Behaviors and Developmental Disorder of Hippocampus in Zinc Finger Protein 521 (ZFP521) Mutant Mice
por: Ohkubo, Nobutaka, et al.
Publicado: (2014)