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Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus

Diffuse alveolar haemorrhage (DAH) is a rapidly developing condition owing to a lack of effective treatment and resulting in a high mortality rate in systemic lupus erythematosus (SLE). Neutrophil extracellular traps (NETs) contain numerous antigens and proinflammatory substances that directly damag...

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Detalles Bibliográficos
Autores principales: Han, Xinai, Zhang, Xiaoming, Song, Rui, Li, Shiqi, Zou, Shujing, Tan, Quanguang, Liu, Tianyang, Luo, Shugeng, Wu, Zhe, Jie, Hongyu, Wang, Jinhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995194/
https://www.ncbi.nlm.nih.gov/pubmed/36910905
http://dx.doi.org/10.1155/2023/4743975