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H3K4me3 regulates RNA polymerase II promoter-proximal pause-release

Trimethylation of histone H3 lysine 4 (H3K4me3) is associated with transcriptional start sites and has been proposed to regulate transcription initiation(1,2). However, redundant functions of the H3K4 SET1/COMPASS methyltransferase complexes complicate the elucidation of the specific role of H3K4me3...

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Detalles Bibliográficos
Autores principales: Wang, Hua, Fan, Zheng, Shliaha, Pavel V., Miele, Matthew, Hendrickson, Ronald C., Jiang, Xuejun, Helin, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995272/
https://www.ncbi.nlm.nih.gov/pubmed/36859550
http://dx.doi.org/10.1038/s41586-023-05780-8