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H3K4me3 regulates RNA polymerase II promoter-proximal pause-release
Trimethylation of histone H3 lysine 4 (H3K4me3) is associated with transcriptional start sites and has been proposed to regulate transcription initiation(1,2). However, redundant functions of the H3K4 SET1/COMPASS methyltransferase complexes complicate the elucidation of the specific role of H3K4me3...
Autores principales: | Wang, Hua, Fan, Zheng, Shliaha, Pavel V., Miele, Matthew, Hendrickson, Ronald C., Jiang, Xuejun, Helin, Kristian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995272/ https://www.ncbi.nlm.nih.gov/pubmed/36859550 http://dx.doi.org/10.1038/s41586-023-05780-8 |
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