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Functional interaction between Vangl2 and N-cadherin regulates planar cell polarization of the developing neural tube and cochlear sensory epithelium

Although the core constituents of the Wnt/planar cell polarity (PCP) signaling have been extensively studied, their downstream molecules and protein–protein interactions have not yet been fully elucidated. Here, we show genetic and molecular evidence that the PCP factor, Vangl2, functionally interac...

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Detalles Bibliográficos
Autores principales: Nagaoka, Tadahiro, Katsuno, Tatsuya, Fujimura, Kyoka, Tsuchida, Kunihiro, Kishi, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995352/
https://www.ncbi.nlm.nih.gov/pubmed/36890135
http://dx.doi.org/10.1038/s41598-023-30213-x