Alpha fetoprotein promotes polarization of macrophages towards M2-like phenotype and inhibits macrophages to phagocytize hepatoma cells

Alpha-fetoprotein(AFP) is a cancer biomarker for the diagnosis of hepatocellular carcinoma(HCC); however, its role in macrophage polarization and phagocytosis remains unclear. In the present study, we explored the correlation between AFP regulation of macrophage function and the possible regulatory...

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Detalles Bibliográficos
Autores principales: Zhang, Minni, Liu, Kun, Zhang, Qiuyue, Xu, Junnv, Liu, Jinchen, Lin, Haifeng, Lin, Bo, Zhu, Mingyue, Li, Mengsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995430/
https://www.ncbi.nlm.nih.gov/pubmed/36911723
http://dx.doi.org/10.3389/fimmu.2023.1081572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995430/
https://www.ncbi.nlm.nih.gov/pubmed/36911723
http://dx.doi.org/10.3389/fimmu.2023.1081572

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