Fine mapping and accurate prediction of complex traits using Bayesian Variable Selection models applied to biobank-size data

Modern GWAS studies use an enormous sample size and ultra-high density SNP genotypes. These conditions reduce the mapping resolution of marginal association tests–the method most often used in GWAS. Multi-locus Bayesian Variable Selection (BVS) offers a one-stop solution for powerful and precise map...

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Detalles Bibliográficos
Autores principales: de los Campos, Gustavo, Grueneberg, Alexander, Funkhouser, Scott, Pérez-Rodríguez, Paulino, Samaddar, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995454/
https://www.ncbi.nlm.nih.gov/pubmed/35853950
http://dx.doi.org/10.1038/s41431-022-01135-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995454/
https://www.ncbi.nlm.nih.gov/pubmed/35853950
http://dx.doi.org/10.1038/s41431-022-01135-5

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