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Fine mapping and accurate prediction of complex traits using Bayesian Variable Selection models applied to biobank-size data
Modern GWAS studies use an enormous sample size and ultra-high density SNP genotypes. These conditions reduce the mapping resolution of marginal association tests–the method most often used in GWAS. Multi-locus Bayesian Variable Selection (BVS) offers a one-stop solution for powerful and precise map...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995454/ https://www.ncbi.nlm.nih.gov/pubmed/35853950 http://dx.doi.org/10.1038/s41431-022-01135-5 |