Imputation-powered whole-exome analysis identifies genes associated with kidney function and disease in the UK Biobank

Genome-wide association studies have discovered hundreds of associations between common genotypes and kidney function but cannot comprehensively investigate rare coding variants. Here, we apply a genotype imputation approach to whole exome sequencing data from the UK Biobank to increase sample size...

Descripción completa

Detalles Bibliográficos
Autores principales: Wuttke, Matthias, König, Eva, Katsara, Maria-Alexandra, Kirsten, Holger, Farahani, Saeed Khomeijani, Teumer, Alexander, Li, Yong, Lang, Martin, Göcmen, Burulca, Pattaro, Cristian, Günzel, Dorothee, Köttgen, Anna, Fuchsberger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995463/
https://www.ncbi.nlm.nih.gov/pubmed/36890159
http://dx.doi.org/10.1038/s41467-023-36864-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995463/
https://www.ncbi.nlm.nih.gov/pubmed/36890159
http://dx.doi.org/10.1038/s41467-023-36864-8

Ejemplares similares