Genistein mitigates senescence of bone marrow mesenchymal stem cells via ERRα-mediated mitochondrial biogenesis and mitophagy in ovariectomized rats

Senescence of bone marrow mesenchymal stem cells (BMMSCs) induced by chronic oxidative stress is an important factor contributes to the postmenopausal osteoporosis (PMOP). Mitochondrial quality control takes a pivotal role in regulating oxidative stress and cell senescence. Genistein is a major isof...

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Detalles Bibliográficos
Autores principales: Li, Mengyu, Yu, Yejia, Xue, Ke, Li, Jiayi, Son, Geehun, Wang, Jiajia, Qian, Wentao, Wang, Shaoyi, Zheng, Jiawei, Yang, Chi, Ge, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995482/
https://www.ncbi.nlm.nih.gov/pubmed/36871183
http://dx.doi.org/10.1016/j.redox.2023.102649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995482/
https://www.ncbi.nlm.nih.gov/pubmed/36871183
http://dx.doi.org/10.1016/j.redox.2023.102649

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