Neuroprotective effect of Dl-3-n-butylphthalide against ischemia–reperfusion injury is mediated by ferroptosis regulation via the SLC7A11/GSH/GPX4 pathway and the attenuation of blood–brain barrier disruption

BACKGROUND: Stroke is one of the most severe diseases worldwide, resulting in physical and mental problems. Dl-3-n-butylphthalide, a compound derived from celery seed, has been approved for treating ischemic stroke in China. No study has evaluated how Dl-3-n-butylphthalide affects the ferroptosis SL...

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Detalles Bibliográficos
Autores principales: Xu, Shuangli, Li, Xuewei, Li, Yutian, Li, Xiangling, Lv, E., Zhang, Xiaojun, Shi, Youkui, Wang, Yanqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995665/
https://www.ncbi.nlm.nih.gov/pubmed/36909944
http://dx.doi.org/10.3389/fnagi.2023.1028178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995665/
https://www.ncbi.nlm.nih.gov/pubmed/36909944
http://dx.doi.org/10.3389/fnagi.2023.1028178

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