Cargando…

Synapses, predictions, and prediction errors: A neocortical computational study of MDD using the temporal memory algorithm of HTM

INTRODUCTION: Synapses and spines play a significant role in major depressive disorder (MDD) pathophysiology, recently highlighted by the rapid antidepressant effect of ketamine and psilocybin. According to the Bayesian brain and interoception perspectives, MDD is formalized as being stuck in affect...

Descripción completa

Detalles Bibliográficos
Autores principales: Sherif, Mohamed A., Khalil, Mostafa Z., Shukla, Rammohan, Brown, Joshua C., Carpenter, Linda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995817/
https://www.ncbi.nlm.nih.gov/pubmed/36911109
http://dx.doi.org/10.3389/fpsyt.2023.976921