Highly efficient export of a disulfide‐bonded protein to the periplasm and medium by the Tat pathway using CyDisCo in Escherichia coli

High‐value heterologous proteins produced in Escherichia coli that contain disulfide bonds are almost invariably targeted to the periplasm via the Sec pathway as it, among other advantages, enables disulfide bond formation and simplifies downstream processing. However, the Sec system cannot transpor...

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Detalles Bibliográficos
Autores principales: Arauzo‐Aguilera, Klaudia, Saaranen, Mirva J., Robinson, Colin, Ruddock, Lloyd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995818/
https://www.ncbi.nlm.nih.gov/pubmed/37186227
http://dx.doi.org/10.1002/mbo3.1350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995818/
https://www.ncbi.nlm.nih.gov/pubmed/37186227
http://dx.doi.org/10.1002/mbo3.1350

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