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Barbiturates and pyrazolopyridines for the treatment of postpartum depression—repurposing of two drug classes

Zulresso (brexanolone) is an aqueous formulation of the neurosteroid, allopregnanolone, and the only FDA-approved medication for the treatment of postpartum depression (PPD). While brexanolone is effective for the treatment of PPD, lengthy infusion time and high cost can be prohibitive. Failure of G...

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Detalles Bibliográficos
Autores principales: Horwitz, Alexander B., Rubin, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9995982/
https://www.ncbi.nlm.nih.gov/pubmed/36909181
http://dx.doi.org/10.3389/fphar.2023.1139889