Integrating copy number data of 64 iAMP21 BCP-ALL patients narrows the common region of amplification to 1.57 Mb

BACKGROUND AND PURPOSE: Intrachromosomal amplification of chromosome 21 (iAMP21) is a rare subtype of B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). It is unknown how iAMP21 contributes to leukaemia. The currently known commonly amplified region is 5.1 Mb. METHODS: We aimed to narrow down...

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Detalles Bibliográficos
Autores principales: Hormann, Femke M., Hoogkamer, Alex Q., Boeree, Aurélie, Sonneveld, Edwin, Escherich, Gabriele, den Boer, Monique L., Boer, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996016/
https://www.ncbi.nlm.nih.gov/pubmed/36910655
http://dx.doi.org/10.3389/fonc.2023.1128560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996016/
https://www.ncbi.nlm.nih.gov/pubmed/36910655
http://dx.doi.org/10.3389/fonc.2023.1128560

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