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Integrating copy number data of 64 iAMP21 BCP-ALL patients narrows the common region of amplification to 1.57 Mb
BACKGROUND AND PURPOSE: Intrachromosomal amplification of chromosome 21 (iAMP21) is a rare subtype of B-cell precursor acute lymphoblastic leukaemia (BCP-ALL). It is unknown how iAMP21 contributes to leukaemia. The currently known commonly amplified region is 5.1 Mb. METHODS: We aimed to narrow down...
Autores principales: | Hormann, Femke M., Hoogkamer, Alex Q., Boeree, Aurélie, Sonneveld, Edwin, Escherich, Gabriele, den Boer, Monique L., Boer, Judith M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996016/ https://www.ncbi.nlm.nih.gov/pubmed/36910655 http://dx.doi.org/10.3389/fonc.2023.1128560 |
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