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Osimertinib Improves overall survival of EGFR-mutant NSCLC patients with leptomeningeal metastases
OBJECTIVE: Osimertinib is a third-generation, irreversible, small-molecule epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that can effectively penetrate the blood brain-barrier (BBB). This study mainly explored the factors affecting the prognosis of EGFR-mutant advanced non-...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996091/ https://www.ncbi.nlm.nih.gov/pubmed/36867956 http://dx.doi.org/10.1016/j.tranon.2023.101637 |