Pan‐Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival

Genetic alterations in cancer cells trigger oncogenic transformation, a process largely mediated by the dysregulation of kinase and transcription factor (TF) activities. While the mutational profiles of thousands of tumours have been extensively characterised, the measurements of protein activities...

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Detalles Bibliográficos
Autores principales: Sousa, Abel, Dugourd, Aurelien, Memon, Danish, Petursson, Borgthor, Petsalaki, Evangelia, Saez‐Rodriguez, Julio, Beltrao, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996241/
https://www.ncbi.nlm.nih.gov/pubmed/36688815
http://dx.doi.org/10.15252/msb.202110631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996241/
https://www.ncbi.nlm.nih.gov/pubmed/36688815
http://dx.doi.org/10.15252/msb.202110631

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