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Computational exploration of molecular flexibility and interaction of meropenem analogs with the active site of oxacillinase-23 in Acinetobacter baumannii

Background: Carbapenem-resistant Acinetobacter baumannii is an opportunistic pathogen responsible for nosocomial infections and is one of the biggest global threats according to the World Health Organization (WHO), particularly causing substantial morbidity and mortality. Objectives: This study aime...

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Detalles Bibliográficos
Autores principales: Ramachandran, Balajee, Muthupandian, Saravanan, Jeyaraman, Jeyakanthan, Lopes, Bruno Silvester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996302/
https://www.ncbi.nlm.nih.gov/pubmed/36909706
http://dx.doi.org/10.3389/fchem.2023.1090630