Cargando…
Common framework mutations impact antibody interfacial dynamics and flexibility
INTRODUCTION: With the flood of engineered antibodies, there is a heightened need to elucidate the structural features of antibodies that contribute to specificity, stability, and breadth. While antibody flexibility and interface angle have begun to be explored, design rules have yet to emerge, as t...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996335/ https://www.ncbi.nlm.nih.gov/pubmed/36911727 http://dx.doi.org/10.3389/fimmu.2023.1120582 |