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Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia

Acute myeloid leukemia (AML) is challenging to treat due to its heterogeneity, prompting a deep understanding of its pathogenesis mechanisms, diagnosis, and treatment. Here, we found reduced expression and acetylation levels of WISP2 in bone marrow mononuclear cells from AML patients and that AML pa...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Song, Wenjun, Ma, Xinying, Yu, Mingxiao, Chen, Lulu, Tao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996369/
https://www.ncbi.nlm.nih.gov/pubmed/36736423
http://dx.doi.org/10.1016/j.jbc.2023.102971